Milk teeth – Photo: EuroNews
Human clinical trials for Redevelopment are expected to begin in July 2024.
by page euro news, The study, led by the Kitano Hospital Medical Research Institute in Osaka, Japan, aimed to provide “a new drug for the treatment of patients with missing adult teeth due to congenital factors.”
Dr. Katsu Takahashi, chief of oral surgery at the Kitano Hospital Medical Research Institute, has been researching the drug since the 1990s.
Supported by the Japan Agency for Medical Research and Development (AMED), his research team has successfully induced the growth of “third generation” teeth on animals – first followed by baby teeth and then primary teeth. Permanent maturation – on animals.
By developing a neutralizing antibody drug that blocks the action of USAG-1, a gene that inhibits tooth development in humans and mice, the team induced tooth regrowth in mice and ferrets.
The promising results of the study are published in a scientific journal NatureAttracting the attention of the global scientific community.
according to the newspaper Mainichi (Japan), the research team is taking steps to prepare this drug for human use.
Once its safety and effectiveness are confirmed, it will first be used to treat children aged 2 to 6 years who have symptoms of anodontia (the medical term for the absence of sufficient teeth). Then there are those who have lost their teeth due to decay or serious reasons. dental disease
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