There have been 3 European studies showing that mixing AstraZeneca and Pfizer vaccines produces good resistance – Photo: news.com.au
On September 9, many Australian newspapers cited sources of scientific weekly news Nature said researchers from Saarland University (Homburg, Germany) found that mixing two vaccines AstraZeneca and Pfizer/BioNTech produced a better immune response against COVID-19 than when using one.
This is the third clinical trial this year to demonstrate the benefits of COVID-19 vaccine mixing, following the studies of the Institute of Health. Carlos III (Spain) in May and Oxford University (UK) in June.
Talking about the latest discovery, professor Peter Collignon, an Australian infectious disease expert, said the results were promising, but more research was needed on the long-term (immunological) benefits as well as the side effects of mixed vaccinations.
“The indications are positive, but we need to gather more data from the facts to not just rely on lab results, and to make sure there’s nothing unusual about safety,” said Professor Collignon. determined.
The Spanish and British studies included 400 and 460 people, respectively. The size of the German study is similar.
Notably, the German trial did not record more severe side effects of the vaccine mixed (compared to using the same vaccine).
Journal Nature comments: “Studies to date have involved only a few hundred participants, which means they are too small to detect rare reactions such as blood clotting, estimated to occur with a probability of 1 in 50,000 after the first dose of AstraZeneca, and 1/1.7 million after the second dose”.
“The numbers look good, but we don’t know how effective the long-term protection will be. We need to test in the real world to see if there is any difference, we are intending this.” Dr Rod Pearce, former president of the Australian Medical Association, said.